产品货号：
Z15860
中文名称：
DISC1抗体
英文名称：
Anti-DISC1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DISC1 Antibody |
| 指标别名 | C1orf136;DISC1;DISC1 long;disrupted in schizophrenia 1;KIAA0457;SCZD9 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | DISC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human DISC1(461-477aa EKQQLQKEIEALQARMF),different from the related mouse sequence by two amino acids,and from the related rat sequence by four amino acids. |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DISC1(Disrupted in Schizophrenia 1),is a protein that is encoded by the DISC1 gene in humans.Ma et al.(2002) determined that the mouse Disc1 gene maps to chromosome 8 in a region with homology of synteny to human chromosome 1q42.Ozeki et al.(2003) demonstrated that rodent Disc1 expression displayed pronounced developmental regulation,with the highest levels in late embryonic life during development of the cerebral cortex.Millar et al.(2005) showed that DISC1 interacts with the UCR2 domain of phosphodiesterase-4B,implicated in susceptibility to schizophrenia,and that elevation of cellular cAMP leads to dissociation of PDE4B from DISC1 and in increase in PDE4B activity. |
| Uniprot ID | Q9NRI5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | disrupted in schizophrenia 1 |
| 蛋白名全称 | Disrupted in schizophrenia 1 protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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